NAD+:
Nicotinamide adenine dinucleotide (NAD) is a coenzyme molecule that works with the mitochondria that is found in every cell of the body. Mitochondria are membrane-bound cell organelles that generate most of the chemical energy needed to power the cell’s biochemical reactions. Naturally found in every cell in the body that can maintain DNA integrity and reverse cellular damage. NAD levels naturally decline as we age.
Due to its ability to bind to and stimulate the activity of other enzymes, NAD+ is classified as a “helper molecule.” Involved in nearly 500 enzymatic events, this potent molecule helps the body stay healthy and functional by supporting the following processes.
Research has shown that NAD+ levels in the body are directly related to the intensity and duration of an immunological response to infection. During an infection, macrophages benefit from elevated levels of NAD+ because it enhances their ability to neutralize the invading pathogen.
Human cells need energy and if NAD+ levels are low, the body’s ability to make and use energy is hindered. The reactions (Glycolysis, Krebs cycle, oxidative phosphorylation, and fatty acid oxidation) by which the body produces and utilizes energy all depend on NAD+ and low amounts of this cofactor interfere with energy metabolism.
Genetic expression refers to the process by which the instructions contained in the DNA of cells are translated into the proteins and other substances that the body needs. The successful expression of genes is achieved through NAD+-dependent modification of histone. Since NAD+ is required for this reaction, low amounts of this cofactor may interfere with this process and, in turn, reduce the efficiency with which genes are expressed.
Maintaining enough NAD+ levels is crucial for the health and survival of brain cells. This was reinforced by studies that showed that after a severe neurological event, NAD+ was important in regenerating the brain’s neurons. NAD+ decreases the progression of neurodegenerative disorders by enhancing the body’s natural capacity to repair damaged cells. Also, If NAD+ levels are increased, it leads to the accumulation of proteins that help with cellular communication and improved cognitive function.
Multiple essential bodily functions depend on NAD+ and would grind to a halt if NAD+ production were to cease. NAD+ promotes healthy senescence, aids in the repair of damaged DNA, increases cellular resistance to stress while shielding brain tissue, and regulates our eating and sleeping habits to meet our physiological demands.
When levels of NAD+ are low, the best approach to guarantee total bioavailability of NAD+ is by intravenous infusion or intramuscular injection. This implies that your body will be able to take in and use the maximum effective dose of supplementary coenzymes. The anti-aging, immune-boosting, and metabolism-boosting effects of NAD+ therapy make it a top choice for replenishing low levels of NAD+.